Yes. It is unthinkable that Bayern Munich, who have been impressive this season, finally suffered their first defeat this season against Mainz in a surprising way. This defeat made Bayern Munich's hopes of matching Leverkusen's unbeaten record last season finally disappear. Indeed, this defeat did not change Bayern Munich's ranking in the standings, they remain solid at the top, but this defeat should be a self-reflection for Kompany to be more serious in strengthening the defense line.
Bayern Munich becomes different without Kane, although they created many chance, but if there's no one able to score a goal, the chances become useless. Muller didn't play bad, he's a false nine. I think Bayern Munich don't need to make it complicated, for sure the upcoming match they might likely lose since they meet Leipzig. But Kane and Coman will available in the next year, so Bayern Munich will play with their best eleven.