The injuries Kane and Neuer have had a significant impact on Munich attack and defence at the moment, although they are still able to dominate the game and create many chances in each match but the effectiveness in their attack is very low compared to when Kane played, the defeat to Mainz has broken their positive trend in the Bundesliga at the moment, so I think Kompany might implement a different strategy for the next match, because in my opinion Kompany needs to find a solution to improve his finishing, and of course a change in strategy and giving other players the opportunity to change in the attack is a possible thing to do.
After the absence of Kane and Neuer in the match, Bayer Munich and Mainz looked very down in the final finishing so Bayer Munich had to accept defeat in that match. I think Kompany has a new plan and strategy in the next match, yes of course Kompany will make new changes by replacing him. a player who can adapt attacks like kane, let's see whether Kompany will design a new strategy or still stick with the old formation.
Of course Kompany has to make changes because it is impossible for them to continue to rely on Kane in the front line and when Kane is absent, Bayer Munich's performance is quite bad in the front line.
I think that so far Kane has always been the difference and made a big contribution in the front line so that if Kane is absent, the Bayer Munich team seems to lose direction and that was proven in the match last weekend when they had to suffer their first defeat in the Bundesliga this season.
For the next match, Kompany must be able to make significant changes and must be able to return this team to its best performance to win, otherwise the competition for the Bundesliga title will be increasingly difficult.