The injuries Kane and Neuer have had a significant impact on Munich attack and defence at the moment, although they are still able to dominate the game and create many chances in each match but the effectiveness in their attack is very low compared to when Kane played, the defeat to Mainz has broken their positive trend in the Bundesliga at the moment, so I think Kompany might implement a different strategy for the next match, because in my opinion Kompany needs to find a solution to improve his finishing, and of course a change in strategy and giving other players the opportunity to change in the attack is a possible thing to do.
After the absence of Kane and Neuer in the match, Bayer Munich and Mainz looked very down in the final finishing so Bayer Munich had to accept defeat in that match. I think Kompany has a new plan and strategy in the next match, yes of course Kompany will make new changes by replacing him. a player who can adapt attacks like kane, let's see whether Kompany will design a new strategy or still stick with the old formation.
Bayern Munich without Harry Kane seems to have lost an effective attacking force, nothing will change if Harry Kane is still absent, I think Kompany will still use the same formation, but Kompany will definitely change his strategy because the previous strategy was very vulnerable to being defeated by his opponent, the defeat against Mainz was Bayern Munich's first defeat and it will be used as evaluation material for Kompany to plan a better strategy, but in a few days Bayern Munich will have to face Leipzig in the Champions League if without Harry Kane I'm afraid they will lose, especially since Leipzig has not won in the Champions League, he will definitely try hard to beat Bayern.