Lazio, Tottenham and Galatasaray are still strong challengers for Manchester United so facing them is not an easy matter and Manchester United's condition which has not fully improved will actually be a worry when they will face one of the three teams. Amorim must maximize the Europa League because this is the only way that might bring them to the Champions League and if they can maximize it well, the opportunity will open up. But it should be remembered that coming out as champions is not easy because we can see how Leverkusen, who performed very well in the previous season in the Bundesliga, failed because they lost to Atalanta in an unpredictable way.
I don't even believe that Man United can win the title here and I believe more in Lazio or Galatasaray whose performance is more consistent.
If Man United can qualify for the next round, surely when they meet some of the teams you mentioned, Man United will definitely get strong pressure. While MU's defense is very weak and has not been able to be fixed by Amorim at this time.
I say that Man United's chances of winning the title here will be very difficult.