You don't bet on sports you are not familiar of simply because it will only make you lose more than making you win. But always prefer to know your sport preference first and stick to it, otherwise your money will only go to waste since you risk your funds betting on a sport that you know nothing about.

However, there's one advantage if you bet on an non-familiar sport, you will be force to learn that kind of sport so you won't be at loss anymore the next time you decide to bet on it.