I do not think so, there is really not that much "toughness" going with these both clubs to be fair. I have seen what Dortmund is capable of and Leverkusen is capable of and that's why I do not think that it will be that much of a big deal. Obviously it is going to be a tough deal with time but we need to consider how this could be changing with time as well.
I believe that Leverkusen will do fine and they will end up getting a win without a doubt. So that is the most important part, if we can keep doing this then we are going to end up with a much better situation. Betting on Leverkusen looks like a simple situation, there isn't really a complicated deal at all and it is so obvious that we are going to see this changing with time so we can definitely see this so easily.
If we would be in the last season and that game comes on the next weekend i would say yes it would be a easy win for Leverkusen without any doubts.
But this season is different and Leverkusen have got there struggles at some games , and also other teams have there problems.
So you cant say that it will be an easy win for Leverkusen on friday against and in Dortmund.
I still go for Dortmund this time but all is possible.