OP, please give us more detail. For example,
1. What is the name of wallet, exchange, software or service did you use?
2. Have you tried searching your email, browser history or your computer/phone for any hint or information about your Bitcoin?
Also wallet like bBockstream Green has 2FA wallet. It has both 2-of-2 and 2-of-3 2FA wallet. But it is still the same question which is the seed phrase needed to recover the coins if it is a noncustodial wallet.
For non-custodial wallet with 2FA, brute-forcing the encrypted wallet file is also an option.