Between the two options of winning or losing because if the draw is no longer hopeless, then the match against Club Brugge should be able to win at home.
I think Pep Guardiola should focus on this match first because it concerns them in order to qualify for the playoff phase, maybe in this match they can win at home, if for example they lose then it means that Manchester City's ability is still below.
The game against Club Brugge will be difficult especially when things are not really going well and their win against Chelsea doesn't really mean it will be better because we saw the disappointing performance of the Blues on that game. I believe the Club Brugge team/manager must have watch the match between City and Chelsea, and must have seen the errors by the Blues thereby making ways to avoid them.