When gamblers takes loan to gamble they will not gamble with a clear mind, they will gamble with the mindset of making profits so that they might clear a little bit of their loan. However it's not guaranteed that they might win so gaming with interest mindset on dept money will do no good to a gambler. Ths why it's very important not to gamble with a loan money. If gamblers wants to gamble with a loan money it means they could not afford it, that's why they borrowed to satisfy their gambling urge.
Many gamblers behave carelessly if they have experienced a big loss or are addicted to gambling, namely by borrowing money to be able to gamble and hoping to get a profit or return their losses, but gambling is a risky game so there is no guarantee that the money can be returned or not, even spending a lot of money cannot guarantee that your money can be returned, so someone who gambles by borrowing money is the same as committing suicide because the possibility of experiencing even greater losses.