Changes will only happen with the clubs on second and third positions exclusive the first position. Real Madrid was able to manage with their poor form initially in Laliga, and they're still first on the table. Compared to now that Real Madrid is getting more stonger, and you expect that Atletico Madrid or Barcelona will dethrone them from the first position, I doubt it.
I am also inclined to think that Real will not miss out on their opportunity and will be able to hold their position until the end of the season. I had my doubts about Atletico from the start, but I thought that Barcelona with Flick would achieve everything in La Liga this season, but I see that they very often lose points in matches where they should not have done so. I can’t say that Barcelona is in worse shape than Real, but they are not stable enough to stay at the top.