Porto have a better record for head to head against Roma, Roma have recorded two wins, two draws and a defeat to Roma. The home side has shown resilience in their recent fixtures and have proven to be a stronger side playing at home with a good home record compared to Roma's away performances. I predict Porto to get a win against Roma in their Europa League meeting.
Porto are a better club in history than Roma but with very rising form of Roma recent months with Claudio Ranieri, Porto will have to be fully focused and carefully with AS Roma. I can not say between Porto and AS Roma, what team are stronger than another, but assume they are almost the same in quality, their matches will hardly be decided a winner in each match.
Porto better record against Roma can increase the motivation of the players to extend their positive record, the factor of playing at home also has a big influence for them. However, Roma performance has also been slightly better since being handled by Ranieri, Porto must be able to maintain improving their performance in this game because lately they have had difficulty winning.
In my opinion, the strength of both teams is quite balanced, only luck can lead Porto to victory because in their last 8 matches in all competitions, they have only managed to achieve 1 victory.
Football is amazing in a way that even between two equal teams, result can be very different match by match, as it can end as a draw, a minimal win, or a landslide win when one team perform perfectly and another team collapse. I am thinking about two very tight matches between Porto and AS Roma and perhaps they will have to fight at penalty shootout spots too.