Even if they will play at home, it won't bring a big impact because they can't play with their ideal lineup. Some players are forced to play not in their best position, ex: Tchouaméni and Valverde. This will make the players probably to play under his performance and they can't optimize the contribution the the team. 
There's nothing special about playing at home actually so Bernabeu could even offer a defeat if the don’t perform well but for some reasons maybe, it jas always been different against mancity.. perhaps this time will be different because of the week defence yet Mancity defence is kinda weak and it has been reflecting in most of their game since Dec 2024, so many lose even to sole unexpected team so the main reason why i will still choose to stay neutral. Things could be different though maybe the first leg will tell alot of it 
Real Madrid has too many missing players. In my opinion, Manchester City is in an advantageous position for the first leg. These disadvantages of Real Madrid may cause them trouble. Manchester City and Pep Guardiola know Real Madrid well and I am sure they will act with a team lineup that suits Ancelotti. That is why I think Manchester City has the advantage.
but i hope you know their current situation as well.. i will still choose to stay neutral on sides to win maybe after the firtleg . I support a team already though but it all "hope of winning "