In the last 5 year both teams have been meet several times in this competition and the match between them always be tight and hard to predicted this because both teams considered as favourite champion and this is early meet for them because i expect Manchester City and Real Madrid will meet at round of 16 or if possible at the final match
Both teams can no longer meet in the final, this game is a two-legged knockout game, one team will advance to the next phase and the other will be eliminated. Looking at the performance of both teams in this competition, I don't see them getting far, for example, if Real Madrid advances to the next phase, they will face strong opponents who, if they play poorly, will lose. The same will happen with Manchester City if they advance to the next phase.