Galatasaray might win the match but qualifying to the next round is still a big challenge to them because of their defeat away from home with three goals which seems very hard to score.
AZ Alkmaar was stronger than Galatasaray in the first leg and I still believe that those same players are the ones going to play the match. This might not make any difference in Galatasaray performance but with Osimhen presence, we might see a little difference.
Galatasaray's defeat in the first leg was quite big. It will be difficult to catch up on the goal difference in the second leg. Even with Osimhen in the team, their chances of qualifying are indeed small. Unless AZ really plays badly without tactics, and that allows Galatasaray to score a lot of goals. But we know that's not possible. AZ being able to win in the first leg is clearly a confidence booster for them in the second leg. I think even if Galatasaray wins, they won't make a big goal difference.
Only a few teams are able to turn things around when they are 3 goals behind in the first leg, but there is no harm in keeping faith, who knows Galatasaray will be lucky in the second leg. Playing in front of their own supporters will certainly give them more confidence, especially since Osimhen is reportedly available again. However, on the other hand, Okan Buruk will most likely lose his other attackers, Alvaro Morata and Mauro Icardi due to injury. Galatasaray real problem lies in their defense, they concede goals too easily.
AZ Alkmaar will carry out a safe play mission, they no longer need to force themselves to win, a draw or a loss by a margin of 2 goals will still take them through to the last 16. The Eredivisie representatives also benefit in terms of match schedule, they have more time to prepare a strategy because there is no match schedule in the middle of the week. In my opinion, Galatasaray has a higher chance of winning in the second leg, but I also doubt they can catch up on the 3-goal deficit.