This is not exactly a charity, but it is a worthy cause in my view. An open source movie is in the works that wants to portray life in a resource based economy and the idea of a better world for all people. I have recently persuaded them to accept bitcoin donations for their work. For those of you who are interested in donating to or following the progress of this project, I highly encourage you to check out their sample video and take note of their current and ongoing accomplishments.

http://www.wakingupmovie.com/2011/12/bitcoin-donations/