For team performance and the number of players who suffered injuries to each team will definitely affect because if that happens then the opportunity for any team to qualify for the semifinals will be a little more difficult. Liverpool are still on a positive track to compete for titles and vice versa with PSG which may for now they will fight hard to achieve better results, even though it is not easy to do because competition in the next round will definitely be far more difficult.
PSG can be far more focused because in Ligue 1 has no big challenges to get a trophy because the challenger is not so strong to pursue the points they have collected. But Liverpool will get a much more fierce competition so that their focus will certainly be divided into the two competitions. If the wrong step will make the opportunity disappear and the match will become more difficult because the victory in the first leg will determine and PSG is a little more benefited for playing at home.
Injuries and how well teams play will definitely affect their chances of making it to semifinals making competition even harder. Liverpool and PSG are both trying to win titles but they are in different situations. PSG can focus only on this competition because they are already ahead in their own league Ligue 1. On the other hand Liverpool has to deal with very tough competition in Premier League which might make it harder for them to focus on both competitions. If they make one mistake they might lose their chance and game will become even more difficult. Result of first game will be very important and PSG might have small advantage because they get to play at home.