I will leave this for someone else to confirm anyway, but I believe using one's profile address when requesting a withdrawal makes the withdrawal request to be processed much faster than when using any other address.
I don't know either. Maybe using a different address from the profile address increases the probability of the withdrawal being flagged to be reviewed manually. Just a guess.
I just know that in the case you use your profile address, you don't need to verify your withdrawal via email even if you don't have 2FA enabled.