PSG will not lose the Ligue 1 title. PSG is ahead of the second-placed team in the table by a large margin. PSG is ahead by 13 points. Each team will play 10 more matches. It is not possible for Marseille to reduce the 13-point gap in these 10 matches.
They can lose Ligue 1 title in other seasons but not in this season when they have played well and now managed 13 points more than Marseille. The Ligue 1 season only has 10 more match days and with 13 points more than a latest competitor Marseille, it's very big and enough for a strong team like PSG to secure and take a league title.
Now Luis Enrique will definitely try his best to do well in the Champions League. But in the next match of the Champions League, PSG is going to face a strong team like Liverpool. Liverpool is very strong this season. Liverpool is able to perform well in both the Champions League and the Premier League. It is not easy for PSG to win against such a team. PSG is more likely to lose in this match.
Luis Enrique is aware of his main task with PSG, managing the club and helping them to win a first ever Champions League title in their club history. They hired him because of his good record and Champions League title with Barcelona, and so far he has yet succeeded with this ambitious task. Luis Enrique knows that if he continues his failure to help PSG winning Champions League, the club owner will sack him in future.
Meeting Liverpool in round of 16 is very unlucky draw for PSG but the draw happened, the pair was set and PSG have to accept it, prepare their best for these two coming matches with Liverpool that will decide their season is successful or failed.