It was a bad match for Lille against PSG last weekend. They are going into the Champions League match with a negative situation, but their opponent Borussia Dortmund is far from their old days in the Bundesliga. If it was last year's Borussia Dortmund, I would say they would easily pass this round, but the current situation is far from certain. We all saw that Atalanta was the favorite but was eliminated by losing in both matches. So it would be very wrong to talk about a match with certainty. Both teams are very strong and both teams will have a good fight.
In their last 5 games Dortmund has only 1 lost but Lille has 3 so there's no way that Lille can be in a better position going into this game. Dortmund is going to win Lille in both legs or are you forgetting how good Dortmund has been in the champions league recently. They almost won it last season and will be looking to attempt that again. It's only bigger clubs that'll become a problem for Dortmund and not smaller clubs that they've not been favourites in the champions league. I don't think Dortmund will be leaving in the round of 16, maybe in the quarterfinals or semis finals. Both clubs aren't in a good form but Dortmund is the bigger and favourite club to win.
There are also differences in squad quality. Borussia Dortmund has a stronger squad. Lille has a more modest squad. When this is the case, Borussia Dortmund is automatically the favorite. The team that will probably win the matches and advance to the next round will be the German team. They have been doing well recently and their performances have been on the rise. I think they will continue this rise with Lille.