It's obvious that in gambling their's always a fear if you will win or not, some people doesn't take as precaution, for me, I know quite well that when you're over conscious of gambling that might lead to make a mistake, because I know already that in gambling despite how far you gone in gambling or experience you have gotten on gambling when you stake high amount of money you most definitely be afraid of losing
Sometime the fear can make some people to pay attentions to correct their predictions, and sometimes also make some people to be bias in prediction and that will lead to make a mistake, so since gambling is assured for you to win, definitely you most be afraid of losing when you stake with high amount as I said initially.
The key phrase in your post seemed to me, where you talk about the fear of losing about a large bet amount, if this causes fear, then it would be reasonable to avoid this combination, just do not make large bets that you are afraid of losing. You should always strive for comfort, everyone can start listening to themselves, when we do something that we do not like you will feel internal resistance, listen to yourself and do not do what you do not like or if you are afraid of the consequences. No need to chase one big win, break the bet into many small bets and reduce the risk of losing everything in one bet.
You're right, or better still he can go for single bet since he is always scared of losing in a large bet. So I think the best way is to go for single bet at least this can reduce some fear, since it has to do with only one single game. Is obvious that the reason why most people always choose multiple games is because they can't afford to stake with Bigger amount, because going for a single game always requires staking with a huge amount of money so as to boost the odd, and this is also very risky. So why can't you just Stick to single game, then you can decide to stake with the amount you can easily afford, instead of going for large bet.