Liverpool's next match will face Southampton and Everton in the Premier League so it will be a little easier for them to get full points because the opponents they face are not too strong and even Southampton itself is the weakest team in the Premier League at this time.
It is not too difficult for Liverpool to beat Southampton who are currently languishing at the bottom of the standings, but Arne Slot will not take any risks in this game because he must keep his core players fit to face PSG in the second leg of the UCL. Rotation will be carried out in several positions to prevent their mainstay players from getting tired or in the worst case scenario getting injured, but Liverpool must still prioritize their goal of getting three points to prevent Arsenal from closing the gap on them.
Liverpool still needs this 3 point in other to secure there chance of lifting the premier league trophy so I think they will make use of there good or key players even if is not all and win and the fact that Liverpool is at home surely they will win and Liverpool is more inform than Southampton this season and even if Liverpool coach decides to rest all his key players I'm not sure Southampton will still be able to win Liverpool, Southampton is the last in the table with just 9 point and if you check there last five match Southampton has lost 4 matches and just won 1 and Liverpool has won 4 matches and draw 1 and if you check there five last head to head matches between this two teams Liverpool has won 4 and draw 1 with them from all this statistic you will find out that Liverpool has more chance to win Southampton, Arsenal is not a consistent team so even if Liverpool rest there key players and end up drawing this match Arsenal won't still be able to top, but I will advise Liverpool to try in winning this match for me I will predict Liverpool to win is impossible for Southampton to win, well good luck to both team.