The matches between Atletico versus Real Madrid, and Liverpool versus PSG will be the main highlights in the second leg. Of course, those two matches are quite difficult to predict, and may require a lot of consideration if want to bet. Meanwhile, Arsenal, Bayern Munich, Inter Milan, and Aston Villa are basically in a fairly safe position, with the goal margin advantage they got in the first leg. Barcelona, despite having a 1-0 advantage over Benfica, also has a good chance of advancing to the quarter finals. Another match that is difficult to predict is the match between Lille versus Dortmund, perhaps in the end the Ligue 1 representative will succeed in eliminating Dortmund, because Niko Kovac squad is currently in very poor performance
Not entirely sure about the Real vs ATM one, surely Real would be a lot better, they are just looking like a much better team so I am not guessing that we are going to see that much of an issue for them to win, and I am not aware of any missing players neither so it shouldn't really be a problem neither.
We are going to end up with Real having a go at ATM that should be a much better one without a doubt, I can't see Simeone figuring out how to beat Real Madrid in this situation. Liverpool and PSG situation could be a lot more closer depending on how Liverpool plays, if they play like they did all season then Liverpool could win easily but if they play like last game then PSG will have a shot at winning the game.