The second leg of Real Madrid vs Atlético Madrid is definitely difficult to predict as the odds are not very wide. The odds of the two teams are close, but the bookies have tipped Real Madrid to win. Since this match is at Madrid's home ground, they will enjoy the advantage and will be strong in defense and attack. Every match in the Champions League is very difficult, but I think Real Madrid have a lot of experience as they have won the UCL many times. And for Atlético Madrid, Ancelotti will definitely try to adopt a different strategy and build a strong team to enter the quarter-finals.
I expect a surprise from the second leg where Atletico Madrid is able to beat Real Madrid because in the second leg Atletico Madrid still has a big chance to advance to the next round. However, beating Real Madrid is not easy because Real Madrid's defense is very strong so Alvarez et al must be able to find a gap to score early. This season Simeone has a good chance in the Champions League and La Liga so he must bring his team to be able to focus well.
But seeing Real Madrid's game in the first leg, of course the obstacles for Atletico Madrid in the second leg are quite big. Because they have to be able to play as well as possible in securing their defense from attacks by Real Madrid players. Mbappe must be stopped because he is so agile in finding gaps to score goals. If only Atletico Madrid managed to beat Real Madrid, Manchester City fans would be very happy with this because Manchester City was eliminated by Real Madrid this season.