The condition is clear but it won't be easy for Roma, and they can look at Liverpool that needed a draw at their home stadium, but they failed at home and eliminated by PSG. Roma's task is more difficult than Liverpool's task because they will play home away in this second leg and Bilbao already shown their quality in Rome last week.
Roma only need a draw but Bilbao have good attacking power and at their home stadium, they will challenge Roma a lot there. Ranieri is very experienced and he used many alternative players last weekend in a match against Empoli as preparation for this big match with Bilbao. Hopefullly he can bring Roma to quarter finals in Europa League.
I don't think Roma will make the same mistake as Liverpool. I have seen Roma's performance in the last few matches. We can really see an unprecedented improvement in the performance of this team. Roma has been winning for a long time in Serie A and this team is consistently able to play well. We also saw Roma's organized gameplay in the home match against Athletic Club and Roma won.
Bilbao's home match in the second leg. Of course, Bilbao will try their best to win. Such matches are naturally fiercely competitive. Both teams have the possibility of winning. Bilbao and Roma are not weak teams. Even then, I will put Roma ahead. However, my prediction is that the match will end in a 1-1 draw.