Lille are very strong when playing at home, even in the European Champions League, they have had better results when playing at home, that's why I also hope to see them come out with a win. I also bet on Real Madrid to win
My predictions for today's games
Lille - Borussia Dortmund (Lille will win)
Atletico Madrid - Real Madrid (Real Madrid will win)
Aston Villa - Club Brugge (draw)
Arsenal - PSV Eindhoven (draw)
Are your predictions for regular time or including AET as well? If all of them are for regular time then it looks like quite a risky one.

But maybe it's what you are looking for today I don't know.
Lille is a good choice. I also think they'll win. I didn't like Dortmund in the 1st leg. They should have won that. Lille can eliminate them by a win.
Real Madrid to win in regular time is very risky and I don't think it'll even happen. A draw might be seen in regular time or maybe Simeone will even surprise us.

The remaining two choices could win. Arsenal might make a rotation. Club Brugge have to win by some gap to come back but it's a really tough job.