Lille vs Borussia Dortmund will be a fierce match because both teams have almost the same strength and Agg is also still a draw because when the first leg both teams played 1-1, and for the second leg later Lille is indeed slightly favored to win because they are playing at home.
However, for betting options I think it is quite risky to bet on Lille's victory, because no matter what Borussia Dortmund cannot be underestimated, I think it is better to bet on over goals in this match because it is quite possible to happen considering that both teams have great ambitions and have quite balanced strengths.

And for the Madrid Derby I think the same, this is a fierce match between two teams that still have the same possibility to qualify so anything is possible.
In this match I also bet on over goals, I am sure there will be many goals scored in the match later.

For Arsenal and Aston Villa, I think it will be an easy match for both teams, especially since Arsenal and Aston Villa are already ahead on Agg in the first leg and in the second leg they will play at home, so I think Arsenal and Aston Villa will be able to win the match easily.