I don't think that Everton will make things difficult for Liverpool, because Liverpool will use the anger and frustration of getting kicked out from UCL to dismantle Everton defense. Since Liverpool is no longer in any European competition again, they will have all the time devoted to winning EPL. I will bet on Liverpool to win the match, because they're the best in EPL currently.
There is no doubt that Liverpool are the best in the Premier League this season because it is also clearly seen from the number of points that Liverpool have earned this season. But for the Liverpool vs Everton match, it is a match at the beginning of next month so there is still a lot of time to discuss this because before that Everton also have to host West Ham United in the match this weekend. And indeed if you look at the quality of Everton's game this season, of course there is no great potential for Everton to beat Liverpool at Anfield.