Well Tottenham had a lot of troubles against AZ and they struggled a lot it was seen in the first leg,now again Frankfurt its gonna be really close and it can go either way. The easiest opponent on paper Lazio has. Bodo/glimt aint that good and Lazio must take advantage of this.
Against Frankfurt will certainly be more difficult. Because Frankfurt seems to be quite strong this season. Even Ajax was also rendered helpless in the round of 16. Frankfurt won with a quite striking aggregate of 6-2. Meanwhile, for Tottenham, they had quite a hard time against AZ, even in the first leg, Tottenham lost. Luckily, Tottenham managed to turn things around in the second leg by scoring 3 goals.
I personally really regret that AS Roma had to lose in a way that I didn't really like. Well, AS Roma lost to Bilbao because in the second leg AS Roma almost played with only 10 players. The red card that Hummels received in the 11th minute was really a sign that AS Roma were unlucky this time.