If you are a bettor, this will be a good chance to bet on Eintracht as they are the underdog here. And if you feel, they have the chance to beat Tottenham, go for it. In this game, everything is possible. Just remember, getting one goal would need hard work from the players. Eintracht has their chance here but need to watch the performance of the players as you will have the idea if they can really overpower the strength of Tottenham guys.
The only reason I will be having expectations for Tottenham to win over Frankfurt is because the English Premier League teams have a special way of play that makes it difficult for team from abroad to compete against them. Tottenham might not be doing so well in the EPL and be winning games in European competitions it has been happening on quite enough occasions so it is possible that Spurs can get a win in this fixture.
Also, the only way for Tottenham to play in the Champions League next year is to win the Europa League this year. We can say the same thing for Manchester United. That's why English teams give so much importance to the Europa League. Tottenham will want to advance as much as they can in this cup. They have to prepare better than ever for the Frankfurt match and they have to beat Frankfurt both in Germany and England. If that happens, their seriousness for the cup final will be revealed.