Both Manchester United and Tottenham are underperforming in the Premier League. That's why their target is to win the Europa League and qualify for the Champions league. But that's also very difficult.
Manchester United will play against lyon in the quarter-finals. lyon is a strong team. This team has performed well in the Europa League platform and even in the last few matches of Ligue 1, Lyon's players have been able to play well.
Tottenham is going to play against frankfurt. Frankfurt is one of the most renowned teams in the Bundesliga. Frankfurt has qualified for the quarter-finals by defeating a strong opponent like Ajax. So this team cannot be underestimated in any way.
Manchester United and Tottenham are teams that have good quality overall and what happens in the domestic league will be different from what happens in the Europa League so it cannot be used as a reference and even in the last few seasons we often see teams that win the Europa League do not have a good ranking in the final standings of the domestic league maybe that will also happen to Manchester United or Tottenham.
For the opponents that will be faced in the quarter-finals I think all teams have equal quality and also in terms of percentage all teams have the same possibility to be able to win the match and advance to the semifinals.