When important people are questionable to suit up I never place a bet on the team. I mean you can just wait until some minutes before the game when the final roster available gets published, there are many fantasy sports sites that bring updates super quick actually. Also on Twitter teams often make a post about the starting 5 minutes before the game starts. That's the safest route. I had my fair share of bad surprises when suddenly some main guy didn't suit up and my bet was doomed before the game even started.
This is a good suggestion which I’m not aware until you brought up, I thought fantasy sports usually just have virtual players like NBA2K that doesn’t reflect the actual roster that will play on the game.
I’m only relying on the google stats when the game is started that’s why I rarely bet on prematch because some questionable players usually play/not play unexpectedly on the actual match.
The odds variation is just minimal factor to consider if the questionable players usually play gives a huge impact on the game.