If Manchester United cannot win this cup, this season will be a very unsuccessful season, and they are aware of that. That's why they will do whatever it takes to be successful in Europe.
Maybe their current target in the EPL is just not relegated. They are trying to keep getting points without big targets. Then they focus on the Europa League. Maybe realistically the Europa League still has many different opportunities than the EPL. After this season ends, maybe Amorim will make a lot of big changes. Amorim may take advantage of the transfer market to add strength next season. It looks like they will suffer the same fate as Arsenal or Chelsea are in the bottom of the table. Against Nothingham is realistically maybe 1 point to take home.
Mathematically there is no possibility for Manchester United in the Premier League this season, they are already very far behind and maybe trying to avoid the relegation zone is a realistic thing for them.
This weekend Manchester United will visit Nothingham's headquarters this weekend, it is really a very difficult job because Nothingham's performance is very impressive this season so I think there is no need to expect more for the results of the match, maybe getting 1 point is very good for Manchester United.
And for the focus of Amorim's team, of course, they will focus very much on the Europa League competition because only in that competition they have a good possibility and also there is great hope to be able to get a ticket to the Champion League next season by winning the Europa League title this season, so of course that will be their main target now that is possible to achieve.