Head to head doesn't make sense when it is European teams playing each other. It is even funny, those are just last 5 games, with one of them the most recent being in 2023 and the last one is 2004. Some of those players might literally dead. I do not see why head to head matters in these type of games, it obviously doesn't matter, and should be ignored.
What matters is their games this season, and if they played against any similar teams before, then that matters too. I saw how Lyon plays, and I saw how United plays, I can tell you that even on a bad day, United is still not that bad, but on a good day, they are so much better than Lyon, not even close. So that is why I will bet on United to win both games this time.