The odds on Man City winning are high, around 2.2... Which also gives us reason to wonder about their chances of winning... But it seems to me that such high odds are a gift... Here and in La Liga in the match with Atletico Madrid the odds are high for the favourites to win... Man City have a great motivation to stay in the UCL zone... Man U do not have any motivation, on the contrary they need to keep their energy before the Europa League match... I think Man City will win...
Manchester City have a motivation to qualify for Europa or Champions League, while Manchester United have a motivation to proves everyone wrong because they always carry pressure to win every match. 
I predict the match will end in draw.
The odds for Atletico Madrid to win is high because their recent performance are poor and their head to head, total draw and win are similar. Hence the odds draw isn't high, anything can happen.