I don't think these two teams can give Real Madrid or Barcelona a hard time. Real Madrid and Barcelona will win these matches without any problems. Also, since the situation is at a critical level in the league, I think Real Madrid will play the matches more focused and win most of their matches. The Arsenal defeat may have been a shake-up match for them. Perhaps such a defeat was necessary on the way to becoming a strong Real Madrid again.
Leganes and Alaves are the teams at the bottom of the standings, they should not trouble Barcelona and Madrid. This week should be 3 points for them. Atletico will also face a weak team Valladolid, it should not be a threat to them and the standings will not change for this week. Barcelona will still be at the top, followed by Madrid and Atletico.
I think it will be a match week where all three teams will win. Of course, Real Madrid will have a very difficult match because they have to rest their players for the Arsenal match. If they do not rest their players, they will not be able to find that little hope in the Arsenal match. If they do not take the field with their main squad, there is also the risk of losing points. Of course, Real has a very good squad, but small teams can always be challenging.