Bitcoin is risky so one should not invest in risky sector like Bitcoin with loan from bank. We know investing in Bitcoin requires long-term planning. Now if you take a loan from a bank you have to repay it within a certain period, but you may fail to repay the loan. However, I don't invest more money than I can afford to lose, I invest some money from my income, so why should I take a loan from a bank? You cannot guarantee 100% profit by investing in Bitcoin. So I think you should not invest by taking loan from bank.