I completely agree — no one has really explored this area deeply. That’s likely because of the overwhelming complexity, which discourages many due to the sheer scale of the mathematical research required. But if someone dares to explore any possibilities or probabilities hidden in this mountainous domain, it should be encouraged — not criticized or dismissed.
Sorry but you are mistaken.
The fact that SHA256 is a non reversible algorithm with no link between inputs and outputs (and with uniform distribution) has not only been proven mathematically, but this proof has stood the test of time for 25 years.
Bitcoin relies on that. So if you think prefixes (inputs) have ANY impact on their sha256 (outputs) it means you break this sha256 proof, which again, has been made by cryptographers 10 leagues above anyone posting in this thread.
I'm not one to crush dreams, by all means, have fun with it.