There is a very thin line between the greed and the risk in this case. The reason is that if you do not take profits at certain key levels then it is highly likely possible that bitcoin may not move further and you miss out taking profit and holding your coins for another bear market.
Greed and risk have a correlation. When you become more greedy, it will be riskier.
Wise investors probably will plan for taking profits into several targets. This way will reduce the risk level and avoid being too greedy. We won't miss the chance for taking profits because we accumulate it gradually into several level of prices. For example if we have 100% of Bitcoin investment. We may set a target for taking profits 50% when Bitcoin crossed $100k, 25% when Bitcoin reaches $120k, and 25% when it hits $150k.
I wouldn't call it a risk nor I will call it a greed but I will call it a sensible way of exiting at the top. No one can call the exact top, it's all speculations.
Not sure what we can call it. But when people are trying to set a target for profits at a very high price, it will be riskier. When you can deal with the level of the risk, then it is okay to set the target. Sure, it is all speculation, there is no exact goal in Bitcoin investment. We have no guarantee for profits! However, for the safety reason, always makes realistic goal for taking profits.