Most of those coins do not even have a road map or use case and their price will eventually get flatlined. Avoid extreme greed and seek for projects which at least over a bare minimum of utility and future.
Not even a paper, and if they have one, they are just copy-paste or upgraded versions of dead coins' versions. They thrive on the story behind the meme; just take a look at TrumpCoin and Mubarak. They attached it to personality and events, and since there is no use case, they thrive on hype, and early investors and whales are the winners once the dump starts to happen.
There is profit in investing in memes, but its nature is very similar to gambling; it really depends on luck.