They will not do that unless they learn from their losses.
The ideal stoppage is when they have nothing left and they'll not do anything to stop when they still have money left.
No one can beat them and so the casino will do it for them. realization is hard and they should make themselves aware of that before the baddest situation comes.
One can't always learn the hard way; we can still try to beat that temptation of always trying so hard to beat the casino until we lose all our balance and are left with nothing before the person can realise his or her self, which is when they can accept the fact that the casino is winning over them. It's hard to deal with it, but some can always make the best decision of walking away and taking a break to rethink before coming back with a more positive mindset.