On the long run, players are the ultimate losers, this is why I choose to be a humble gambler who risk very small money, people critize me because I choose to risk too very little money, they keep saying I won't win a lot, but I don't care, because the roller coaster never ends.
The caveat in gambling, just like in trading too, is to stake what one can afford to lose. It doesn't matter whether it's small amount or not. For me, I don't think those who even stake little amount are better off than those who stake large funds. Just make sure what you're staking isn't something that gives you nightmare. If it does, it simply means you're over staking your funds. What I frown at in gambling isn't the amount that's staked but addiction. Amount staked is relative to gamblers. Every gambler should define their risk appetite by themselves.
Those who stake little amount always regret it when they hit wins. If one must eat a frog, why not eat the rotund ones? That's my philosophy.