What is an insitution wants to buy $1billion of bitcoin. How many sats is that???
100M sats is equal to 1 BTC. You do the math.

I kind of like the idea for making it seem affordable for retail to jump in but not sure it's practical.
Do you think pricing by sats is a good idea?
It's fine, but either is fine if it's going to be still with btc and then some decimal points. What matters is the adoption that's happening from these institutions. They surely want to have Bitcoin as much as they can. And I think that there was already a discussion like this in the past about what Bitcoin will be called by the majority if it's not a whole one and just sats or mBTC.