There is only one handicap for Chelsea here. They played a Champions League decider match in the Premier League 2 days ago. The fatigue will be their biggest enemy. If they deal with it well then I don't think there will be a surprising result.
It's obvious the difference in quality but we never know where the surprise will be, will Chelsea lose? That would be normal in my opinion.

The Premier league decider made Chelsea more determined to win and now they're doing that job again this final so I think Chelsea will win this one.
I wouldn't even be surprised if Chelsea lost dramatically.
Chelsea will use this final match as an opportunity to collect the European Conference League trophy into their cupboard because next season they will no longer play in this less important league in Europe because the level is below the UEFA Europa League. Chelsea may only get that chance once.
The losing position will be number two and I won't be surprised either. But if you think about it, the final situation later if Chelsea will win, it means that the dominance of the English Premier League is quite strong in the 2024/2025 season.