Before I proceed with that question, please let me know how experienced you are in creating a paper wallet.
It's generally not recommended for beginners to make a paper wallet, as it can be quite risky.
If you do create one, consider depositing a small amount for testing purposes.

Important details on how to secure your private keys have been mentioned and linked above.
As long as you make multiple copies and store them securely in different locations to prevent total loss, you should be safe.

IMO, due to their fragility, many now prefer hardware wallets or metal backups that are more resistant to fire, water, and corrosion than paper.