Bitcoin holding should last at least 5 to 10 years or longer before you can even think of taking profit, because take profits when your bitcoin investment is not up to 5 years it is not a good holding and even taking profits at early stage of accumulation is also a bad investment unless you are a trader, only traders panic and sell when bitcoin price is decreasing. as far as you an investor you don't have to panic and sell when bitcoin dip rather buy those dips and hold for bitcoin price will increase with time just keep buying bitcoin and hold.
That is boring for someone like me who has only small amount of Bitcoin holdings on my portfolio because you know the profit would be very small but when you usually take profit everytime there is an opportunity there is a higher chance that it will be getting better because price goes up and down and regardless of trend you can always get profit from it depending on what strategy you are using. I once hold but missed to take profit before price tank and yeah it took me a long time to break even because my funds are pinned. So for me much better to take profit.