For some reason and all of the sudden Iran's nuclear program is a major concern, but for years during the Obama and Biden administrations (and even during Trump's first,) it wasn't. Whether Iran's nuclear program is seeking energy independence or weapons capability is open for debate, and from the perspective of most Americans, if of little concern.
What's interesting is that Iran's nuclear program has been the most transparent and most restricted in the world. Majority of IAEA inspections are from Iran and the largest number of inspectors and the agency's surveillance equipment are installed in Iran to monitor it 24/7! And despite having the right to enrich Uranium to any percentage like 90%, Iran has been voluntarily accepting restrictions to enrich at about 3% among lots of other restrictions for a long time!It was never and is never a concern of anyone. However, it is an excuse for the US regime to be aggressive toward Iranian people and carry out economic terrorism (aka sanctions) against them. Something that all administrations have followed ever since 1979 specifically the trinity you named!
It's pretty much the same tactic they used against Iraq. They just replaced "q" with "n" and used the same lie about WMDs that don't exist. This is why they pronounce Iran wrong and the same way they pronounce Iraq (ie. I-ran instead of e-Run).
The only difference is that when they pushed Iraq, Iraqis budged and disarmed themselves (until eventually got invaded and slaughtered) but when they push Iran, Iranians push back... hard.
Iran wouldn't refer to us as the "The Great Satan" if wasn't for our support of "The Little Satan" constantly creating turmoil in the region.
It is worth clarifying that the Great Satan is referred to the deeply corrupt US regime not the Americans. And there is a good reason for it which is not limited to support of the Zionist child killers. I wrote a short history of it last year dating back to 1940's: https://bitcointalk.org/index.php?topic=5516661.0