Of course, when we only use the amount of money that we can afford to lose to gamble and accept the outcome of the result will help one gamble responsible. This boils down to having self control whenever you are gambling. A lot of gamblers finds it difficult not to think of making profits when they are placing a bet and this can trigger them in using more than the amount of money that they can afford to lose to bet. When they lose their bet, they wouldn't want to let go of their losses.
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I also believe that greed is the main reason for major losses in gambling. The unwillingness to let go of something you’ve already imagined as yours leads to reckless actions and risks you're not prepared for. And by the time clarity comes it’s often too late. That’s why it’s important to have something or someone who can stop you in time, remind you of your limits, and bring you back to reality before the thrill of gambling completely clouds your judgment.