Knowing that there are no guarantees to win on every stake is the reason why people need to take responsible risks. Sometimes gamblers take irrational steps forgetting that gambling is not a sure thing, we've seen a lot of people stake large amounts of certain games and they do so knowing fully well that they are emptying their bank account. The problem most gamblers have is that they don't think of the possibility of losing
You are supposed to gamble with money that you do not mind losing since one cannot influence the results. People have a tendency to forge this fact and lose track getting in much more risk than they can afford. That is when it becomes risky. The point is it is all about how well you are governing your own boundaries and it is very realistic. Accept it as an entertainment but not as a money generating means. Human nature always results in a disaster when they overlook the possibility of losing and large wins to huge bets. And responsible gambling is getting to know the risks and not being blinded by hope.