Losing comes with depressions most times, more especially when you do not take a responsible steps before taking the risks. However, as a gambler the moment you make a mistake about your stake it's obvious that you will lose more than what you can afford to lose. As a gambler you shouldn't risk the last cash in your bank account because you don't know if you might win or not.
However, many players are not stopped by anything, they are ready to risk their entire bankroll in one gaming session, even if they are not very rich. This is because they want to change their lives and have not come up with anything better than playing and betting. Some time will pass and they will find money again and go to play again, it is like a squirrel wheel in which they run, and it rotates in place. Sometimes it would be worth stopping and thinking about some global things that concern gambling, maybe it will completely affect their life in the end.