Winning over a casino is very possible and for those that have won big in gambling even though their overall amount input in all games played cannot be compared to that of the jackpot they won then, they can be celebrated and said to have won over the casino. This only happens in rare cases and I will say it occurs more to those that are smart to always risk small money to win big ones and luck shines on them. A player can win over a casino but the casino cannot lose over to the players because the win of one player cannot be compared to the many losses of players they’ve earned. So technically, casinos can’t lose to players but a player can win over a casino.